Table 3 Baseline characteristics – all female Fontan patients (n = 78)
Pregnant, livebirths (n = 10) | Pregnant, no live births (n = 11) | Never pregnant (n = 57) | ||
|---|---|---|---|---|
Age < 25 yrs (n = 27) | Age ≥ 25 yrs (n = 30) | |||
Age (years)a | 25 (23–38) | 23 (18–32) | 21(20–23) | 29 (27–33) |
Age at first Fontan repair (years) | 9 (3–18) | 7 (3–12) | 4 (2–13) | 6 (5–9) |
Time since first Fontan repair (years) | 14 (11–16) | 17 (13–19) | 17 (14–20) | 25(21–26)b |
Fontan type, n (%) | ||||
Atrio-pulmonary | 5 (50) | 8 (73) | 6 (22) | 21 (70) |
Lateral tunnel | 3 (33) | 3 (27) | 2 (7) | 2 (7) |
Extra-cardiac | 1 (10) | 0 (0) | 19 (70) | 4 (13)c |
Other | 1 (10) | 0 (0) | 0 (0) | 3 (10) |
Functional status, n (%) | ||||
NYHA I | 5 (50) | 3 (27) | 7 (26) | 9 (30) |
NYHA II | 4 (40) | 7 (64) | 19 (70) | 14 (47) |
NYHA III | 1 (10) | 1 (9) | 1 (4) | 6 (20) |
NYHA IV | 0 (0) | 0 (0) | 0 (0) | 1 (3) |
Oxygen saturations, n (%) | ||||
< 85% | 0 (0) | 0 (0) | 0 (0) | 2 (7) |
85–89% | 1 (10) | 2 (18) | 4 (15) | 2 (7) |
> 90% | 9 (90) | 9 (81) | 23 (85) | 26 (87) |
Ventricular function, n (%) | ||||
Good | 10 (100) | 6 (54) | 23 (85) | 22 (73) |
Mildly impaired | 0 (0) | 3 (27) | 2 (7) | 4 (13) |
Moderately impaired | 0 (0) | 1 (9) | 2 (7) | 2 (7) |
Severely impaired | 0 (0) | 1 (9) | 0 (0) | 2 (7) |
Fontan-related complications, n (%) | ||||
Arrhythmias | 0 (0) | 2 (18) | 2 (7) | 14 (47) |
Conduction disease | 0 (0) | 0 (0) | 2 (7) | 5 (17) |
Significant valvar dysfunction | 0 (0) | 2 (18) | 5 (19) | 8 (27) |
Thromboembolism | 0 (0) | 0 (0) | 1 (4) | 5 (17) |
Liver cirrhosis | 0 (0) | 0 (0) | 0 (0) | 1 (3) |
PLE | 0 (0) | 0 (0) | 1 (4) | 1 (3) |
Associated morbidity, n (%) | ||||
Learning difficulties | 0 (0) | 0 (0) | 0 (0) | 1 (3) |
Chromosomal abnormalities | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Pre-pregnancy counselling, n (%) | 7 (70) | 10 (91) | 22 (81) | 28 (93) |